One study included 30 healthy people who had psilocybin inserted into their blood while magnetic resonance imaging (MRI) scanners measured changes in their brain activity. The scans revealed that psilocybin caused decreased activity in what the researchers described as the brain's "hub" regions -- areas especially well-connected with other areas. That study was published in this week's issue of the Proceedings of the National Academy of Sciences.The second study included 10 healthy volunteers and found that psilocybin boosted their recall of personal memories and their emotional well-being for up to two weeks. The researchers said this suggests that psilocybin might prove useful as an adjunct to psychotherapy. That study will be published online Thursday in the British Journal of Psychiatry.A study published last year found that people with anxiety who received a single psilocybin treatment had lower depression scores six months later.
In the 1970s, Psilocybe cubensis mushroom were readily available in rural areas around Dallas-Fort Worth. The best places to search for them were cattle pastures, because the 'shrooms had an affinity for growing in or near "cowpies." When you broke the stem, a slight bluish "bruise" was helpful in confirming the identity. It produced a pleasant psychedelic effect, lasting for a couple hours, but was a bit hard to titrate since the potency of the mushrooms wasn't always predictable.
Or so I've been told.