London, UK - Blood-pressure-lowering drugs should be offered to everyone, regardless of their blood-pressure level, as a safeguard against coronary heart disease and stroke, researchers who conducted a meta-analysis of 147 randomized trials (comprising 958 000 people) conclude in the May 19, 2009 issue of BMJ...Other academics disagree with the conclusion:
"Whatever your blood pressure, you benefit from lowering it further," Law told heartwire. "Everyone benefits from taking blood-pressure-lowering drugs. There is no one who does not benefit because their blood pressure is so-called normal."
Adding his opinion, Dr Franz Messerli (St Luke's-Roosevelt Hospital Center, New York City) said that by including 147 trials in their meta-analysis, the authors had to make numerous assumptions, "some possibly valid, others clearly not."I thoroughly respect the British Medical Journal, but my opinion re this study is expressed in the insert above left. And please note this fine print at the bottom of the page:
Law and Wald disclosed that they hold patents (granted and pending) on the formulation of a combined pill to simultaneously reduce four cardiovascular risk factors, including blood pressure. McManus disclosed that he has a financial relationship with Sanofi-Aventis, Pfizer, A. Menarini Pharma, and Merck Sharp & Dohme.