29 May 2025

Rotate your insulin injection sites


These accumulations of subcutaneous amyloid developed on the lower abdominal wall of a 47-year-old man at the sites of his repeated insulin injections.
"In this case, surgical resection was performed for cosmesis. Histopathological assessment showed amorphous eosinophilic deposits, positive Congo red staining, and apple-green birefringence under polarized light. The specimen also stained positive for thioflavin T under fluorescence."

3 comments:

  1. Aaand now I don't want breakfast.

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  2. This is remarkable, but no one is remarking.
    Reminds me of Men in Black 2...the Ballchinian. 🤷🏻‍♂️

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  3. Oh my goodness, this image led me to the NEJM images page. I used to work in a surgeons office (7-10 general & vascular surgeons) and this brought me right back to the kinds of things we'd see. I guess family doctors would send us anything they didn't know what to do with...

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