17 August 2020

Iota carrageenan depletes alveolar macrophages in vivo


I'm just going to leave this here for now.  It's a board from my poster presentation at the ATS meeting in 1983.  It will be of no interest or relevance to any readers here, but I do use this blog to store some personal memorabilia, and this will allow me to toss out the old posterboard as part of my downsizing.

4 comments:

  1. "no interest or relevance to any readers here"
    sorry, but now I need more info

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    Replies
    1. In the late 70s, I started conducting research in the laboratories of Dr. Alan K. Pierce (Dallas TX), who had a program grant to investigate the biology of the antibacterial defenses of the lower respiratory tract. My focus was on the relative roles of alveolar macrophages and PMNs, and at first I tried to develop an anti-macrophage antiserum as a mouse model for studying respective cellular roles in a dual-phagocyte system. After I moved from Dallas to Kentucky, I tried to use carrageenan to selectively deplete AMs. About that time we found that alveolar lining material was by itself bactericidal vs. pneumococci, which was even more interesting. The time constraints of increasing clinical (ICU), administrative, and teaching duties forced me away from hard science in the lab. And so it goes...

      Delete
    2. Thanks for the context!
      I was in the world of the carregenans but as a food additive

      Greeting from Chile!

      Delete
  2. It’s also good for stabilizing a cheese sauce made with sodium citrate, or maybe I’m thinking about kappa carrageenan.

    ReplyDelete

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